Compound identity
- Designation
- BPC-157 (Body Protection Compound 157)
- Class
- Synthetic linear pentadecapeptide
- Sequence
- Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV)
- Molecular formula
- C62H98N16O22
- Molecular weight
- approx. 1419.5 g/mol (free peptide)
- CAS number
- 137525-51-0
Nomenclature and identity
BPC-157 is the common laboratory name for a synthetic pentadecapeptide. The "157" designation comes from the original naming series used by the research group that first described it. It is sometimes called PL 14736 in the older literature. Research-grade material is typically supplied as a lyophilized solid, often as an acetate salt, so the gravimetric content of a vial includes counter-ion and residual water in addition to the peptide itself.
Because the molecule is a short linear peptide with no disulfide bonds, its identity is usually confirmed by mass spectrometry against the theoretical monoisotopic mass, and its purity by reversed-phase HPLC.
What the published literature examines
Most published work on BPC-157 comes from preclinical animal models and cell-based systems. Reviews summarize investigations into its interaction with angiogenic signaling, nitric-oxide pathways, and tissue models in rodents. A large share of this primary literature originates from a small number of research groups, which reviewers note as a limitation when weighing reproducibility.
A 2025 literature and patent review in Pharmaceuticals (Józwiak et al.) catalogues the range of experimental models reported and the intellectual-property landscape around the peptide. A 2026 review in Pharmaceutics (Mateescu et al.) focuses on biopharmaceutical challenges, covering stability, formulation, analytical characterization, and the translational barriers between preclinical findings and controlled clinical evaluation. Both are reviews; neither establishes clinical efficacy or safety.
Analytical and research considerations
Proline-rich peptides can show broadened or split HPLC peaks depending on mobile phase and temperature, so chromatographic conditions should be reported alongside purity values. Deamidation and oxidation products, truncated sequences from solid-phase synthesis, and residual trifluoroacetate are typical impurity classes to consider when comparing lots.
For quantitative in-vitro work, net peptide content (the fraction of vial mass that is peptide rather than counter-ion and water) matters more than nominal vial mass. Where it is not stated on lot documentation, it should not be assumed.
What a Certificate of Analysis can and cannot establish
A lot COA can
- Confirm that the tested lot matches the expected identity by an orthogonal method such as mass spectrometry.
- Report chromatographic purity (typically HPLC area percent) for that specific lot at the stated test date.
- Tie results to a lot or batch number that can be matched against the vial label.
A lot COA cannot
- Describe any lot other than the one tested, or material after the stated test date.
- Establish biological activity, safety, or suitability for any experimental model.
- Substitute for a researcher's own incoming-material verification where a study design requires it.
Current report status for every catalog item is listed in the Certificate of Analysis library. See also how to read a peptide COA.
Selected independent literature
- BPC-157 as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers.Mateescu DM et al. Pharmaceutics, 2026. PubMed ID 42198317.Review of stability, formulation, analytical, and translational development issues.
- Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review.Józwiak M et al. Pharmaceuticals (Basel), 2025. PubMed ID 40005999.Literature and patent review summarizing reported experimental models.
Literature is cited for scientific context only. Neon Valley Research did not author these publications, and their findings are not claims about any product.
BPC-157 10 MG
Synthetic Pentadecapeptide. Supplied as 10 mg / vial.
- US fulfillment
- UPS Ground $15
- Free US shipping $300+
- Secure card checkout
Related research references
- KPV research referenceThe C-terminal tripeptide (residues 11–13) of alpha-melanocyte-stimulating hormone (α-MSH).
- GHK-Cu research referenceThe copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine.
RESEARCH USE ONLY – NOT FOR HUMAN OR ANIMAL USE. This reference is provided for laboratory and analytical research context only. It is not guidance for any human or animal use.